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John “Scooter” Morris, Tom Ferrin, Tom Goddard, Eric Pettersen, Greg Couch, Elaine Meng, Zach Pearson (UCSF, San Francisco, USA)
Established in 1970, the Resource for Biocomputing, Visualization, and Informatics (RBVI) and its precursor, the Computer Graphics Laboratory (CGL), develops cutting-edge interactive software tools and advanced web-based computational resources that provide integrated visualizations and analyses of molecular structures and related non-structural biological information. RBVI's tools can be applied to diverse types of biomolecular data, including atomic-resolution coordinates, 3D density maps and light microscopy data, and protein and nucleic acid sequences, annotations, and networks. We focus on unmet software needs for basic and applied biomedical research using highly trained and talented staff, with excellent interdisciplinary knowledge and specialized, state-of-the-art expertise in software engineering, computer visualization, and data science. Our primary efforts are in interactive visualization and analysis of structures of molecules and molecular assemblies, protein sequence-structure-function relationships, and network representations of protein similarity, binding interactions, and biological pathways. These areas are critical for addressing important biomedical problems r