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Kari Lavikka, Jaana Oikkonen, Alexandra Lahtinen, Yilin Li, Sampsa Hautaniemi (University of Helsinki, Helsinki, Finland)
As a tumor in cancer grows and spreads, it undergoes a process of clonal evolution, resulting in multiple subclones with different genetic and phenotypic characteristics. To better illustrate the evolutionary relationship of these subclones and their contribution to the clonal composition of tumor samples, we developed a new visualization design: Jellyfish plot. The design supports multiple concurrently sampled tissue sites and multiple sequential time points in the same plot, allowing the reader to gain an overview of the evolution, dispersal, and coexistence of the subclones in the tumor samples of a patient. This poster highlights the design elements of Jellyfish plots and presents multiple examples of their use in visualizing diverse subclonal evolution trajectories.