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Matúš Talčík, Filip Opálený, Tereza Clarence, Katarína Furmanová, Jan Byška, Barbora Kozlíková, David Kouřil (Masaryk University, Brno, Czech Republic)
Chromoskein is a tool we created while researching how to utilize the 3D representation of chromatin fiber. All of it was done in collaboration with biologists. We mainly innovated in 3D rendering, linking data, and user experience. For 3D rendering, we opted for the new WebGPU graphics API to deliver high-performance and aesthetically pleasing results to every user through their web browser. We bind everything together, instantly and bi-directionally. Spotted a curious shape in 3D? Add it to your selection and see it mapped in other viewports. In order to find the shapes in the heavily entangled chromatin, you can create an arbitrary number of cutting planes to see through it. Also, you can decide which parts to hide and which to keep despite the cutting plane. Put together, you should have no trouble inspecting the occluded parts of chromatin. Finally, we know that there is an endless number of genomic formats, so you only need to describe your used format through our UI, and Chromoskein will churn through it. You don't have to hassle with conversions or uploading data to a server.