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Eliot Ragueneau, Noemi Del-Toro, Anjali Shrivastava, Birgit Meldal, Pablo Porras, Kalpana Panneerselvam, Henning Hermjakob (EMBL-EBI, Wellcome Genome Campus, Hinxton, Cambridgeshire, CB10 1SD, UK. Tel: 44 (0)1223 49 44 44)
Molecular Interactions are the physical contacts between molecules and are underlying all cellular processes. IntAct aims to collect and curate those Molecular Interactions. A new website, IntAct Portal, has been developed to easily and intuitively grant access to IntAct’s databases. Its search engine allows to query for molecules, and yield to a network visualisation of all interactions between those molecules and their interacting partners. The network interactors and interactions can be filtered based on their different features which are also displayed in their associated tables. Every interaction evidence is represented by a single edge, and is linked to a detail page which allows to visualise the different molecules that were involved in its discovery, and their contact regions if the detection methods allow it. IntAct is supported by EMBL core funding, Open Targets [grant numbers OTAR-044, OTAR02-048] and Wellcome Trust INVAR [grant number 212925/Z/18/Z]