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Alexandra Pina Kingman, Anne-Kristin Stavrum, Ivan Viola, Helwig Hauser (Thormhlensgate 55, 5020 Bergen Norway)
This image is an excerpt from the animation entitled “Negative charge and poly(ADP)-ribosylation: a scientific animation.” The moecules where uploaded from the Protein Data Bank using the Embedded Python Molecular Viewer plug-in for Autodesk Maya (Johnson et al. 2001; Sanner et al. 1996). The scene was rendered using Maxon Cinema 4D and composited in Adobe Photoshop. Subsurface Scattering was chosen to give the molecules a translucent appearance. Two PARP-1 molecules are shown bound to damaged DNA (Coquelle and Glover 2012). This work has been carried out within the PhysioIllustration project (funded by NFR, project #218023). References: Coquelle, N. and J. Glover. 2012. PARP pairs up to PARsylate. Nat. Struct. Mol. Biol. 19 (7): 660-661. Johnson, G.T. and Autin, L., Goodsell, D.S., Sanner, M.F., Olson, A.J. (2011). ePMV Embeds Molecular Modeling into Professional Animation Software Environments. Structure 19, 293-303. Sanner, M.F., Spehner, J.-C., and Olson, A.J. (1996) Reduced surface: an efficient way to compute molecular surfaces. Biopolymers, Vol. 38, (3),305-320.