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Gagarine Yaikhom (Medical Research Council Harwell, Oxfordshire, Harwell OX11 0RD, United Kingdom)
Genome-wide association studies detect loci that are associated with genetic diseases. This is, however, only the starting point to fully understanding the functions of genes. Uncovering multiple pleiotropic functions of genes is key to deciphering genetic networks and systems that govern developmental and physiological mechanisms. Pleiotropic effects refer to genotype-phenotype mappings where a single locus affects two or more phenotypic traits. From the outset, these phenotypic traits may appear to be unrelated. Exploration, therefore, is key to hypothesis generation. Comparative visualisation enhances analysis by allowing exploratory mixing and matching of genotypes and phenotypes.