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Matthieu Chavent, Marc Baaden, Syma Khalid (Laboratoire de Biochimie Thorique, Paris, France and Systems and Synthetic Biology Modelling Group, Southampton, United Kingdom)
An in silico setup designed to mimic the E.coli outer membrane. The vesicle is composed of phospholipids and a number of E.coli proteins: OmpA, FhuA, OmpF and EspP. The proteins were manually embedded into the vesicle prior to a 1 microsecond molecular dynamics simulation. The system is currently being analysed to study patterns of lipid and protein mobility.