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Dan MacLean (The Sainsbury Laboratory, Norwich, United Kingdom)
The Sainsbury Laboratory has taken on board the techniques and methodologies of genomics approaches. The ballooning of data that the laboratory must deal with is presenting new challenges in data presentation and visualisation. We are interested in using high-throughput sequencing methods to generate new draft genome assemblies from important non-model pathogen species to identify crucial genetic factors for virulence, such as effector genes, that are distinct in pathogen and related non-pathogen species. To achieve this we must integrate large genome assemblies from multiple species and overlay transcriptome and phylogenetic data from multiple experiments. Our current tools include the GMOD project (http://gmod.org) genome browsers and synteny browsers. Our interests in this direction lie in using and developing solutions that can integrate these varied and difficult data into easily interpretable and usable viewers. We have developed gee_fu, a fast, lightweight, extensible genomic feature database and web-service application that is capable of serving next-gen data very quickly. We currently uses the Anno-J display system (