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Peter Sisk, Christian Stolte, Thomas Abeel, Matthew Peterson, Jeremy Zucker, Antonio Gomes, Anna Lyubetskaya, Tige Rustad, Kyle Minch, Irina Glotova, David Sherman, James Galagan (Broad Institute of MIT and Harvard, Cambridge, MA; Boston University, Boston, MA; Seattle Biomed, Seattle, WA)
The first systems-level comprehensive view of the adaptation of M. tuberculosis to stress conditions relevant to pathogenesis provides mechanistic insight into the complex regulation of this adaptation. As a free resource, available to the scientic community through TBDB.org, we presented this complex subject in an easily accessible manner. Integrated into the website are analysis tools designed to turn data into an interactive experience.