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Colin Combe, Marine Dumouseau, Josh Heimbach, Birgit Meldal, Sandra Orchard, Juri Rappsilber (Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3BF, United Kingdom)
The Interaction-Viewer visualizes the contents of PSI-MI (Proteomics Standard Initiative – Molecular Interactions) files as n-ary interactions, rather than binary pairs, removing the need to apply spoke/matrix expansion to data prior to display. PSI-MI is the recognised standard for the capture of molecular interaction data. . The viewer also displays detailed participant information present in these files - such as accession numbers, stoichiometry and positional information about binding sites - as well as added information such as UniProt features and superfamily domains. The specific input data format to the viewer is a JSON object generated by JAMI (https://github.com/MICommunity/PSI-JAMI), a Java application that translates between different PSI-MI data standards. Version 1 of the interaction viewer is in use in EMBL-EBI's Complex Portal (www.ebi.ac.uk/intact/complex), the IntAct Editor curation tool and InterMine's HumanMine (http://www.humanmine.org/). Version 2 will display more information present in PSI-MI files. It will also use the backbone.js library, with the aim of providing a modular data-parsing component that can be used by and shared with other viewers.