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Martina Paganin, Fabio Lauria, Gabriella Viero (via sommarive 18, Trento)
expressyouRcell is a unique and easy-to-use R package which provides an intuitive approach for presenting variations of gene expression levels across time and space. It generates animations of pictographic representations of cells, or pictograms, providing a convenient method for visualizing time course variations in cellular compartments. Dedicated tools to visualize time course variations are still lacking. Few tools have been proposed to display gene expression data directly on cellular pictograms, but the available pictograms are not suitable for representing specific cellular types such as highly polarized cells as neurons, and do not allow the creation of animated pictures. expressyouRcell provides a set of options for creating animated cell pictograms based on different gene expression measures, and on fold changes values, which are particularly useful to highlight the cellular compartments and neuronal structures mostly affected across different experimental conditions. expressyouRcell can generate more effective representations of time course variations in gene expression levels, improving our understanding on several physiological and pathological conditions.