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Diego Pitta de Araujo1, Steven Wolf1, Andrew Wong1, Sruti Jagannathan1, Lakshmi Ramachandran1, Wei Ting Melanie Lee1, D. DuPuy1, Kyaw Tun1, Jean-Francois Rupprecht1, Michael Sheetz1,2 (1 Mechanobiology Institute, National University of Singapore, Singapore; 2 Dept. of Biological Sciences, Columbia University, USA.)
Despite new methods for visualizing cell and molecular processes, the results are often difficult to convey through written forms. Scientists at the Mechanobiology Institute (MBI) in Singapore recognize the need to communicate their science via a compelling story, and there is no doubt that illustrations and animations play an important role in effectively communicating these stories. Research being conducted at MBI is translated into a wide range of visuals, ranging from schematic illustrations to 3D animations and AR/VR models. One key platform to present these visuals is the online educational resource MBInfo (www.mechanobio.info). Here, visuals support descriptions of key cell and molecular processes, and are used to explain new research findings from the institute. We also present a case where 3D animation of protein mechanics has aided the working hypothesis. In the process of “making” the animation, the scientist and the animator explored how Myosin II pulls cellular fibres that lead to cellular movements. With input from the theoretical model, the animator could reveal aspects of the protein mechanics that were not thought previously and bring new insights into the model.