Thumbnails:
List:
Year:
Category:
Session:
Poster:
Getting poster data...
Frederic Fol Leymarie (Goldsmiths, University of London, London, United Kingdom)
FoldSynth is an interactive multimedia platform designed to help people understand the characteristics of protein structures. It uses a simplified model of molecular forces to give an interactive animation of the folding process. The shape of the protein is shown as a 3D visualization floating above a 2D triangular distance matrix [3] which provides an alternative interactive visualisation. The user adds and removes forces by interacting directly with the 3D protein or by "painting" on the 2D matrix. The shape of the protein reacts to the current set of forces with corresponding change to the distance matrix. There are simple tools to paint forces that e.g. cause the creation of alpha helices and beta sheets. Cellular automata can also operate on the distance matrix, introducing dynamic force processes. The forces can be initialized to mimic proteins loaded from a DAS server. The model includes masses and simplified forces for hydrophobicity and electric charge. The 3D visualization shows various representations (smoothed backbone, cartoon, etc.). Forces and properties (such as hydrophobicity) are mapped onto different graphical features (colour, texture, bump mapping) and sonifica