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Derek Wright, Tim Angus and Tom C. Freeman (The Roslin Institute, The University of Edinburgh, Easter Bush, Midlothian EH25 9RG. Scotland, UK)
Biology, in common with many other fields, has experienced an explosion in the availability of high dimensional data over the last decade. This has been primarily driven by the availability of genome sequences and the development of technology platforms that enable the massively parallel analysis of biological components. Analysing and visualizing these data remain a significant challenge. BioLayout Express3D takes a network-based approach to data analysis and visualization. We employ analytical, layout and simulation algorithms, implemented in highly optimized code and rapidly computed using CPU and GPU parallelised computing. We incorporate a range of advanced visualization and animation techniques to support interactive visualization and exploration of very large network graphs in 2D or 3D, generated rapidly and directly from primary data or imported in other common formats. BioLayout Express3D has revolutionized our ability to rapidly and visually interpret large datasets, derived from a range of biological analysis platforms.