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Andy Thomason, Pedro Quijada Leyton, Ioannis Filippis, Michael Sternberg, William Latham, Frederic Fol Leymarie (Goldsmiths College, New Cross, London.)
Bioblox is a playful tool for exploring protein docking using a game-like interface. Designed to open up the world of molecular machinery to a wider audience, our interface reduces a complex 3D process to the pairing of amino acids into a simple docking description which can be shared by social media. Building on our experiences with Foldsynth which pairs amino acids within single strands, we are building a set of tools which allow the public to try their hand at docking molecules. We are exploring visualisations and selection tools that will help to solve complex living jigsaw puzzles by reducing them to much simpler forms. The design goal is to allow any user with an internet connection to pick challenges from the RCSB Protein Data Bank and explore existing and novel configurations of protein complexes while discovering a little of the wonder of the world of molecular machinery. As a result of this we hope to increase public engagement with molecular biology as well as to serve as a testbed for novel metrics and algorithms.