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Ryo Sakai, Matthieu Moisse, Joke Reumers, Jan Aerts (KU Leuven, Leuven, Belgium)
Pipit is a gene-centric interactive visualization tool designed to study structural genomic variations. Typically structural variations are visualized by encoding breakpoints on a linear or circular layout. Instead of focusing on the genomic distance, Pipit visualizes individual genes as a functional unit. Using this visual coding, the focus of the structural variants is shifted from the genomic distance to the biologically relevant feature, i.e. the underlying genes. This visual encoding enables swift visual inspection of genes that are affected by structural variant, detecting the formation of fusion genes or the deletion of dosage-sensitive genes. Pipit is a cross-platform Java application that visualizes structural variation data from Genome Variation Format (GVF) files.