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Wen-ti Liu (Max Planck Institute for Biophysical Chemistry Am Faßberg 11, 37077 Göttingen, Germany)
Ribosome is the biological machinery for protein synthesis. Recently a high-resolution structure solved by single particle electron cryo-microscopy (Fischer et al., Nature 2015) has revealed the important role of ribosomal RNA modification. Certain antibiotics can interact with the RNA modification and therefore interrupt the function of the ribosome.