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Melanie B. Brewer, Gurupartap Davis, Nevan Krogan (The HARC Center and Quantitative Biosciences Institute University of California San Francisco, 1700 4th Street, San Francisco, CA 94158)
In a world of highly complex data, scientific databases and data analysis applications are important. Humans are highly visual and visualization software will be particularly valuable in making data accessible and usable. However, some scientific applications are not as usable as they could be. There is an opportunity to make such tools more effective through human-centered design and user experience methodologies that arose to support development of consumer and enterprise products. We are continuously applying such approaches to development of a scientific data visualization (GPS-Prot; www.gpsprot.org), aimed at displaying HIV-host complexes as well as the human interactome. This web application solves the problem of gathering data from disparate sources and other challenges that represent significant barriers for users to access the information in a comprehensive visualization. Users can enter an HIV or human gene name/ID and instantly search the entire human interactome to discover protein partners as well as explore the entire body of literature supporting each interaction. Some of the challenges unique to scientific UX work and possible solutions are also discussed.