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Imtiaz Khan, Adam Fraser, Mark-Anthony Bray, Paul Smith, Anne Carpenter, Rachel Errington (School of Medicine, Cardiff University, UK; Broad Institute of MIT and Harvard, Cambridge, USA)
Despite the exponential growth of informatics infrastructures and databases, consumption or reuse of biological data beyond the proximity of the data originator is not happening. The inability to depict “experimental design” is considered to be the rate limiting factor for communication, a prerequisite for sharing. Addressing this challenge, we have developed ProtocolNavigator – a virtual laboratory environment that allows emulation of real life laboratory actions. This leads to the automatic representation of a time-integrated, interactive map of an experiment that includes actions, manipulation, and data acquisition signified by familiar icons. Association and sequential analysis of these divulge patterns, which in turn provide a language-independent visual perception of the experimental design. The fully navigable map can be shared with colleagues for design modification and optimization; it can also be converted and printed into any text format for publication. ProtocolNavigator has enabled us to curate and compare practice variation – a quantitative approach for establishing best practice. This we believe is crucial factor for community engagement