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Michael Zyracki, Joseph Schaeffer, Andrew Kimoto, Malte Tinnus, Peter Jones, Dave Parker, Merry Wang (Bio/Nano, Autodesk Research, Toronto, Canada)
3D visualization and design of large biological structures, such as protein data and DNA nanostructures, is integral to applications in research, therapeutics, education, and more. As data becomes larger and more complex, existing industry standard desktop, plug-in, and web-based applications can easily push beyond the limits of advanced in-core processing and rendering. Layered on an extensible cloud-based visualization framework optimized for large 3D models and data, the Viewer demonstrates common usage scenarios of exploration and interaction with molecular data by visualizing large RCSB Protein Data Bank files directly in the web browser. Beyond this, the extensible Viewer framework is being leveraged for a computer-aided design pipeline for 2D, 3D DNA origami designs. The framework can be extended to include other biological data types, enabling future exploration of large-scale, multi-scale, and dynamic models.