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Stefan Simm, Mario Selymesi, Mario Keller, Enrico Schleiff (Department of Biosciences, Molecular Cell Biology of Plants Goethe University, Frankfurt am Main, Germany)
CyanoDB and the implemented graphical user interface (GUI) improve the analyses for cyanobacteria by comprising information about localization, operons, function, sequences, orthologous groups and predicted β-barrel proteins. Genetic features of specific cyanobacteria of seven orders namely Nostocales, Gloeobacterales, Chroococcales, Oscillatoriales, Prochlorales, Stigonematales and Pleurocapsales can be analyzed under the aspect of phenotypical, ecological and physiological diversity. For all orders except of Pleurocapsales at least one species was used to create a pan-genome getting insights in the core-, shared- and specific-genome. The implementation of CyanoDB in addition to the existing CyanoBase (Natao et al. 2010) was required because of the usage of only 37 species within the Cyanobase. In addition, we wanted to extend the pan-genome data with additional information about operons, localization, function and description. CyanoDB was improved by implementing a GUI, which enables the user to set filter for detecting genes of an organism or localization as well as creating subpan-genomes for specific attributes, functions or β-barrel families. Furthermore, the implemhttp://www.uni-frankfurt.de/fb/fb15/institute/inst-3-mol-biowiss/AK-Schleiff/research/index.html