BioLayout Express3D is a powerful tool for the visualization and analysis of network graphs. Network-based approaches are becoming increasingly popular for the analysis of complex systems of interaction and high dimensional data. In biology, networks can be generated from interactions between individuals, disease transmission, sequence similarity, metabolic pathways, protein interactions, pathways, regulatory cascades, gene expression, etc. BioLayout Express3D has been specifically designed for visualisation, clustering, exploration and analysis of very large network graphs in 2- and 3-dimensional space derived primarily, but not exclusively, from biological data.
This tutorial is designed to cover the basics of network visualisation and analysis using this tool with particular emphasis on the analysis of high dimensional data such as that generated by microarray analysis or RNA-seq analyses. If time is available we will also demonstrate the use of the tool in the context of pathway modelling.
Participants will need to bring with them a laptop of any flavour (the program does not run on tablets) with the program and Java installed. To make the most use of the session it would be preferable to have at least a medium range graphics card e.g. AMD or Nvidia and a three-button mouse to allow to exploration of reasonable sized graphs in 3D space.
If in doubt – run the webstart version on the website and if you have any issues or questions contact support@biolayout.org.
Tags: data visualization, networks, tutorial, visualization, VIZBI, VIZBI 2014